Magnetic particles in motion: magneto-motive imaging and sensing

Superparamagnetic nanoparticles have become an important tool in biomedicine. Their biocompatibility, controllable small size, and magnetic properties allow manipulation with an external magnetic field for a variety of diagnostic and therapeutic applications. Recently, the magnetically-induced motion of superparamagnetic nanoparticles has been investigated as a new source of imaging contrast. In magneto-motive imaging, an external, time-varying …

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Development of an Immortalized Porcine Fibroblast Cell Panel With Different Swine Leukocyte Antigen Genotypes

Immortalized cell lines are valuable resources to expand the molecular characterization of major histocompatibility complex genes and their presented antigens. We generated a panel of immortalized cell lines by transfecting human telomerase reverse transcriptase (hTERT) into primary fibroblast cells prepared from ear, fetal, and lung tissues of 10 pigs from five breeds and successfully cultured …

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Recombinant Kunitz-type Soybean Trypsin Inhibitor (r-KSTI)

Kunitz-type trypsin inhibitors bind to the active pocket of trypsin causing its inhibition. Plant Kunitz-type inhibitors are thought to be important in defense, especially against insect pests. From sequence analysis of various Kunitz-type inhibitors from plants, we identified CaTI2 from chickpea as a unique variant lacking the functionally important arginine residue corresponding to the soybean …

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Guideline recommendations and antimicrobial resistance: the need for a change.

OBJECTIVEantimicrobial resistance has become a global burden of inappropriate use of antimicrobials is an important contributing factor. Any decisions on the selection of antibiotic use should take into account the effect on antimicrobial resistance. The purpose of this study was to assess the extent to which the guidelines prescribe antibiotic resistance patterns have been considered …

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Effectiveness of real-time polymerase chain reaction assay for the detection of Mycobacterium tuberculosis in pathological samples: a systematic review and meta-analysis.

Effectiveness of real-time polymerase chain reaction assay for the detection of Mycobacterium tuberculosis in pathological samples: a systematic review and meta-analysis.

Fast and accurate diagnosis of tuberculosis (TB) is the key to managing the disease and to control and prevent transmission. Many established diagnostic methods suffer from low sensitivity or delays in timely results and inadequate for the rapid detection of Mycobacterium tuberculosis (MTB) in a clinical sample of pulmonary and extra-pulmonary. This study examines whether …

Effectiveness of real-time polymerase chain reaction assay for the detection of Mycobacterium tuberculosis in pathological samples: a systematic review and meta-analysis. Read More »

Suggestions for Improving Invited Speaker Diversity To Reflect Trainee Diversity

Suggestions for Improving Invited Speaker Diversity To Reflect Trainee Diversity.

In the field of biomedical research in the United States, the proportion of underrepresented minorities at full professor level remained consistently low, although demographic trainees become more diverse. underrepresented groups face a complex set of obstacles to achieving the status of faculty, including impostor syndrome, increased performance expectations, and patterns of exclusion. institutionalized racism and …

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